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The reaction is monitored by analytical HPLC (46 x 50mm reversed phase Luna C18 column, galvus plus metformin 5 minute linear gradient 1-100%) B buffer, A buffer is water with 01% trifluoroacetic acid, B buffer is acetonitrile with 01 % trifluoroacetic acid)?

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The term “alkthioalkyls” include compounds with an alkyl, alkenyl, or alkynyl group bonded to a sulfur atom which is bonded to an alkyl group. This blocks transcription of the structural genes for both the repressor and the efflux protein.
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Exploratory methods are used to discover what the data seems to be saying by using simple arithmetic and easy-to-draw pictures to summarize data.
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About the book


Sue set sail from England, aged 7, with her parents and younger brother on a dream ocean voyage in the wake of Captain Cook to reach the palm trees, beaches and limitless seafood of the South Pacific, which turned into a 10 year fight through storms, shipwrecks, reefs and limited schooling to break away and get back home.

This is Sue’s story of that trip.  Within a year of setting sail she was injured in a devastating shipwreck in the Indian Ocean and, once recovered, educated herself by post.  Most challenging of all she had to find a way to grow up while being contained with her family in a small space floating around the Pacific Ocean. 


…ambition leads me not only farther than any other man has been before me, but as far as I think it possible for man to go.

The Journals of Captain Cook: The Voyage of the Resolution and Adventure.


It is a simply extraordinary story, outrageous in its breaking all the rules – in 30 years in schools, the most extreme absence I encountered was a family who took their children away for one term for a reasonably safe hike through South America. Fabulous I thought – most fellow heads took a dim view.  The book begs so many questions, not the least educational and how and what we learn and develop.

Sir Anthony Seldon, (Vice-Chancellor, The University of Buckingham) 

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